Hemodynamic Study of the Risk Factors of Intracranial Aneurysm Rupture

The aim of this study is to elucidate the hemodynamic effects of tumor on the risk of rupture of cerebral aneurysms. A three-dimensional reconstruction of the CT images of the patients with the tumor and the non-band tumor was obtained. 3D model-banded tumor and non-band tumor were obtained. The hemodynamics method was used to calculate and the settlement result was obtained by Fluent software. Wall shear stress (WSS), shear stress oscillatory factor (OSI), particle retention time (RRT), and comparative analysis were carried out to obtain the results of band tumor model and non-band tumor model, and the effect of band tumor model on its development mechanism. The results show that the internal flow field of the model is more unstable, and WSS is lower (the maximum WSS of the non-tumor model is 9.5 Pa, and the maximal value of WSS is 6 Pa). At the same time, the model of the band tumor is high and the high RRT area of the band tumor model is much larger than the high RRT area of the non-band tumor model, which indicates that the internal blood flow of the tumor is clutter and is more prone to thrombosis. According to the results, it is concluded that the OSI and RRT of the band tumor model are generally high and the WSS is low, so the conclusion is that the difference of the internal flow field is mainly due to the low WSS, high OSI and the high RRT. The results show that WSS, OSI and RRT are effective indexes to judge the rupture of aneurysm, which is of great significance to the study of the rupture mechanism of cerebral aneurysms.