Mechanical Characterization of Human Ascending Aorta Based on Tensile and Compression Test

To obtain mechanical characterization of human ascending aorta intima, by using the uniaxial tensile system, the mechanical characterization of the human ascending aorta intima were acquired by designed uniaxial and compression tensile test. The maximum rupture force of the human ascending aorta was found to have a positive correlation with thickness. The obtained resulted a significant anisotropy of human ascending aorta intima between circumferential and longitudinal directions, and non-linear stress-strain relationship curve was verified. The maximum tensile stress between longitudinal and circumferential directions of human ascending aorta intima was found that the longitudinal stress was higher. The initial elastic modulus calculated in longitudinal and circumferential directions were 1 104 kPa and 787 kPa. Therefore, the thickness should be taken into account within rupture assessment of aortic intima and the establishment of the human aorta constitutive equation. The primary break continues to tear along the longitudinal direction in the early stage of aortic dissection or aneurysm.