Abstract: This paper presents a new inverted decoupling approach that is suitable for high order multivariable system.In the inverted decoupler,the decoupling elements is independent of the system size,It is more flexible in choosing the transfer functions of the decoupled process.First,according to the relative gain array(RGA),the best pairing for input-output can be obtained,then the expressions of the inverted decoupling are presented for general n×n processes.Second,the stability conditions are stated to select a proper configuration.Finally,the validity can be proved by using several simulation examples,and comparisons with other works demonstrate the effectiveness of this methodology.