Abstract: The recent developments of soft tissue mechanics are summarized. The methods and apparatus of skin experiments in vivo or vitro are introduced. Further, the mechanical and histochemical studies of skin expansion in plastic surgery are explained. For lung tissues, the results of incremental elastic moduli determined by indentation test and obtained from the constitutive equation are compared. Finally effects of storage by freezing, temperature-dependednt properties, aging, stress and motion on the structure and function of tendons and ligaments as well as tissue homeostasis are discussed.