Abstract: To study dynamic response of high-speed slide rail with track irregularity excitation,according to the vehicle dynamic and track dynamic theory,a sled-track dynamic analysis model of the high-speed track system is established.Sled-track dynamic responses under different speeds and irregularity excitations are analyzed and calculated.Effect on sled-track dynamic response by regularity of high-speed slide rail is discussed quantitatively.Results show that the peak vicissitude acceleration is up to 5.1 m/s² when the high-speed sled slides at the speed of 700 m/s.When the sliding speed is 700 m/s,the vibration acceleration of the sled is 8 times than that of 100 m/s.To avoid excessive vibration,the high-speed sled irregularity amplitude must be less than 2 mm.