D<sub>3</sub>-三高立方烷亚甲基上引入硝基的新方法

D₃-三高立方烷亚甲基上引入硝基的新方法

摘要: 报道了一种在D₃-三高立方烷亚甲基上引入硝基的新方法.应用改进的维克托-迈耶反应,成功地将D₃-三高立方烷-4,7-二醇(1)最终转化为4,7-二硝基D₃-三高立方烷(3);将原有方法的五步反应缩短为两步反应,并将总得率由低于15%提高到近30%.

Abstract: A new method for introducing nitro group into the secondary carbons of D₃-trishomocubane is reported. D₃-Trishomocubane-4,7-diol(1) was successfully converted into 4,7-dinitro-D₃-trishomocubane (3) by modified Victor-Mayer Reaction. The total yield was increased from 15% to 30% while the previous required 5 steps was reduced to 2 steps.