Abstract: Much of the early destructions of pavement structure have directly relation with the overload vehicles. The weight of truck is with the development tendency of heavy truck load. This make the overload condition rather more serious. This paper analyzes the destruction of over loaded vehicles for cement concrete pavement on Highway Pingguo-Baise, Guangxi. On the basic of great amounts of data of traffic volume and overload, the influences of traffic volume and truck overload were analyzed, and results of load stress and thickness of pavement are calculated for over loaded vehicles.