Abstract: To study the important influence of interlining on the outcome and provide the theory basis for development of aortic dissection and outcomefor clinical judgment,a model of type-B aortic dissection with different proportions of entrance and export and size of the crevasse by 3D printing was made to simulate the blood flow change and the measure model of aortic dissection false lumen flow field and pressure change.When the true lumen pressure was fixed at 18.620kPa and 21.280kPa, different proportions of breach of the false lumen inlet pressure were generally less than other false lumen locations, and the pressure in the false lumen was lower than the true lumen. When the true lumen pressure was fixed at 23.940kPa, and the crevasse ratio was 2:1,the false lumen pressure on the model compared with other breach scale increased significantly. All true lumen fixed models under the pressure of 21.280kPa and 23.940kPa can be observed that with the same lumen pressure, true lumen flow faster, whose internal pressure was lower than the false lumen. In the same model, the false lumen pressure was generally lower than true lumen pressure. With the same pressure, the false lumen flow rate of the primary break big model was relatively low, the eddy current was obvious. In the same model, with the same pressure, the false lumen flowed lower than the true lumen, the eddy current of false lumen was more apparent, and the complex vortex and the twisting made shock on the cavity wall increasing the risk of fracture.