Abstract: The self-made monolithic catalysts in reverse flow catalytic combustion reactor to explore the feasibility of disposing CO in low concentration was put forward in this paper. A efficient noble metal Pd monolithic catalyst supported by the cordierite honeycomb ceramics after pretreatment was prepared with modified γ-Al ₂O ₃ and light rare earth elements(Ce、La)as auxiliaries. The efficiency of the catalyst in the self-made reactor, the effect of preheated temperature on the monolith catalyst, the effect of the cyclic period and the space velocity on the operation performance of reactor were investigated. Results show that the carbon monoxide conversion efficiency attains 90% when the catalyst preheat temperature is 200℃, reversing cycle is 8min, space velocity is 8000h ^-1, and initial carbon monoxide concentration is 0.1%.