Abstract: In order to take effective steps to minimize the blistering problems on the epoxy asphalt overlays, the cause and propagation mechanism for blisters were studied systematically by means of field investigation, theoretical analysis and mathematical modeling. Based on the theory of thin plate and fracture mechanics,the deflection of blisters was studied under the pressure. Additionally, the energy principle in fracture mechanics was used to derive the energy relationship and the initiation and propagation mechanism was studied. The results indicate that the development of blisters includes three stages, namely, initiation, stale and unstable propagation. The deflection of blisters produced by the external force was related to the radius of blisters, depth and modulus of elasticity of pavement. The energy release rate was proposed as a criterion of the initiation and propagation of blisters. It provides the theory basis for further model experiment and simulation analysis.