Abstract: Removal of toluene by the combination of non-thermal plasma( NTP) and various catalysts was investigated in this study. Self-made wire-cylinder dielectric barrier discharge( DBD) reactor energized by AC power supply was used in our experiment. Specific energy density( SED),energy efficiency(EY) and O₃ concentration of different reactor were investigated. The better catalyst was chosen,catalyst stability test was carried out,and the by-products in the reaction were determined and analyzed. The results show that compared with γ-Al₂O₃,V₂O₅-TiO₂/γ-Al₂O₃ catalysts can enhance the conversion of toluene,decrease SED and O₃ concentration and enhance EY. Stability test of V₂O₅-TiO₂/γ-Al₂O₃ catalyst show that toluene conversion decreases slowly with the reaction time,which indicates that the catalyst suffers slow deactivation,probably due to the accumulation of by-products over the catalyst surface. After calcinations in air for 3 h at 500 ℃,activity of the catalyst can be recovered.