Abstract: There are many studies on the protection of commercial secret in academia, but there are few studies on the protection of commercial secret problems under the so-called “big data” era. This paper mainly focuses on the study of the relationship between commercial secret and data information, the defects of the current commercial secret protection model and the new problems in the protection of commercial secret under the “big data” era. There are many corresponding recommendations from the legislative, administrative supervision and corporate self-prevention in order to improve the current situation of commercial secret protection under the big date era and make up deficiencies, thereby enhancing the competitiveness of enterprises to promote healthily and orderly development of the market.