Abstract: The purpose of carrying out the feasibility study on the cooperation between the university technology zones and the R&D centers of multinational corporations,summing up the experience and lessons learnt from the cooperation in the past is to provide the approaches,ways and relevant policies,which can be used for reference,for the cooperation between them.The research shows that the university technology zones should insist on the opening to the outside world.It's necessary to attract the multinational corporations which are the representatives of the most advanced technology in the world to enter the university technology zones and cooperate in research and development. It accords with not only the trend of the globalization,but also the need of self-development of the university technology zones.It's feasible for the university technology zones in China to cooperate with the R&D centers of multinational corporations and the importance should be attached to it.