Abstract: The speed of policy response in crisis situations is an important topic of research on policy diffusion. Using the COX proportional hazards model in the method of event history analysis, collating into a research framework and assumption of "impact path of organization- institution" "impact path of policy actors" "impact path of policy adaptation attribute" and "impact path of problem-capacity", combining the data of 283 cities across the country on the policy response to the resumption of work and production, this paper deeply analyzes the factors that affect the speed of policy response in crisis scenarios. The research found: (1) From the perspective of time, the response and diffusion of the policy of resumption of work and production is a typical phenomenon of policy outbreaks, showing a significant characteristic of R-shaped curve diffusion; (2) There is a positive correlation between the education of leadership, the numbers of urban industrial manufacturers, the ability to cure patients and the speed of policy response, indicating that these factors have played a significant " acceleration effect" on the speed of policy response; (3) Significant "hysteresis effects" are shown in vertical hierarchy pressure, horizontal regional pressure, local accountability, the severity of epidemic situation and the degree of urban economic development, delaying the city′s policy response speed; (4) There is no significant correlation between the leader age and policy response speed. The analysis of the impact factors of policy response speed in crisis situations provides an empirical data basis for further understanding of policy diffusion speed, and expands the theoretical boundary of research on policy diffusion to a certain extent.