Abstract: The traditional interpretation of the relationship between knowledge and power is exterior to each other and knowledge is independent on the power to obtain the status of epistemology.Rouse as a Philosopher of scientific practice criticizes the opposition of power and scientific knowledge.On one hand,he interprets the scientific practice as a source of scientific knowledge from the dimension of practice;On the other hand,he endows the scientific practice with the power which forms the mode of "power is knowledge".This model for his critical evaluation of science provides a new perspective.