Abstract: With the development is going on globally today, the sovereign nations are facing a kind of difficult position: They hope to participate the international economy mechanism to obtain the common interest and promote their development on one hand, and they worry about the corrosion which is harm to their sovereignty. The article has analyzed dialectical relation between international economy mechanism and nation sovereignty and indicated that the two sides can work well to each other and promote each other. And the article has analyzed the influence and the harm of the neo-interventionism to the international economy mechanism. Then the writer proposed the strategy and the measure for sovereign nation the sovereignty nation should adopt in the participation to international economy mechanism with.