Abstract: Fiber mesh reinforced engineered cementitious composite (ECC) has the properties of high ductility, lightweight, and good durability; however, a single-fiber mesh has limitations in simultaneously improving flexural load and deformation capacity. To solve this problem, tests were conducted to investigate the flexural properties of single and hybrid mesh-reinforced ECC panels through four-point bending tests, and one meshless ECC control panel, four single-fiber mesh-reinforced ECC panels, three carbon and glass fiber mesh hybrid-reinforced ECC panels, and three carbon fiber mesh and steel wire mesh hybrid-reinforced ECC panels were designed. The effects of mesh layers number, types, and mixing methods on the flexural load-carrying capacity and deformation capacity of ECC panels were investigated. The test results show that the carbon fiber-wire mesh hybrid plate gives full play to the advantages of high tensile strength of the carbon fiber mesh and strain hardening of the ECC after the specimen is cracked, which significantly improves the utilization rate of the mesh strength and deformation capacity. When the number of mesh layers is 2, the load-carrying capacity of carbon-glass fiber mesh hybrid plate is increased by 11.98% and the deformation capacity is increased by 13.07% compared with the single glass fiber mesh plate; the deformation capacity of carbon fiber-steel wire mesh hybrid plate is increased by 135.20% compared with the single carbon fiber mesh plate. When the number of mesh layers is 3, the deformation capacity of 2-layer carbon fiber mesh and 1-layer glass fiber mesh hybrid board is 140.89% higher than that of single carbon fiber mesh board; 1-layer carbon fiber mesh and 2-layer steel wire mesh hybrid board are 9.82% higher than that of 1-layer carbon fiber mesh and 2-layer glass fiber mesh hybrid board in terms of carrying capacity, and the deformation capacity is 8.23% higher. The carbon fiber-wire mesh hybrid panel has the best overall bending performance, with similar bending load capacity and better deformation capacity than the carbon-glass fiber mesh hybrid panel. Compared with the single-fiber mesh plate and the carbon-glass fiber mesh hybrid plate, the carbon-wire mesh hybrid tends to slow down the decrease of the specimen's load capacity after the peak load. Based on the test results, a formula for calculating the flexural load capacity was established, and the calculated values agree well with the test values.